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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA2018 All Species: 11.52
Human Site: S989 Identified Species: 36.19
UniProt: Q68DE3 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68DE3 NP_001009899 2242 241153 S989 P C R V E Q D S S D T M Q T T
Chimpanzee Pan troglodytes XP_526444 2043 219516 A847 S V T S E H F A M V A A K S K
Rhesus Macaque Macaca mulatta XP_001106577 2185 234604 T939 D S S D T M Q T T G L L K G Q
Dog Lupus familis XP_545102 2257 241761 T1010 C R V E Q D S T S E T M Q T T
Cat Felis silvestris
Mouse Mus musculus NP_001025060 2221 237469 S988 P C P V Q Q D S L D T M Q T A
Rat Rattus norvegicus XP_001067438 2222 237360 S987 P C P V Q Q E S L D T M Q A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416543 2300 246716 V1052 S V P Q G S S V V M Q D V D L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002666696 2028 217570 S833 S S M N M P M S T T N Q G N C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 94.4 89.4 N.A. 82.8 82.1 N.A. N.A. 66.1 N.A. 35.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 90.5 95.2 92.6 N.A. 88.6 88.2 N.A. N.A. 76.2 N.A. 50.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 0 40 N.A. 73.3 60 N.A. N.A. 0 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 26.6 60 N.A. 80 73.3 N.A. N.A. 0 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 13 0 0 13 13 0 13 25 % A
% Cys: 13 38 0 0 0 0 0 0 0 0 0 0 0 0 13 % C
% Asp: 13 0 0 13 0 13 25 0 0 38 0 13 0 13 0 % D
% Glu: 0 0 0 13 25 0 13 0 0 13 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 13 0 0 0 0 13 0 0 13 13 0 % G
% His: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 13 % K
% Leu: 0 0 0 0 0 0 0 0 25 0 13 13 0 0 13 % L
% Met: 0 0 13 0 13 13 13 0 13 13 0 50 0 0 0 % M
% Asn: 0 0 0 13 0 0 0 0 0 0 13 0 0 13 0 % N
% Pro: 38 0 38 0 0 13 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 13 38 38 13 0 0 0 13 13 50 0 13 % Q
% Arg: 0 13 13 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 38 25 13 13 0 13 25 50 25 0 0 0 0 13 0 % S
% Thr: 0 0 13 0 13 0 0 25 25 13 50 0 0 38 25 % T
% Val: 0 25 13 38 0 0 0 13 13 13 0 0 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _